Brufen 400 mg for Fever: When and How to Use It
Discover how Brufen 400 mg helps reduce fever. Learn its uses, dosage, safety tips, and when to take ibuprofen for effective fever management.

Introduction
Fever is one of the most common signs of infection, inflammation, or immune reaction. It makes you weak, tired, and uncomfortable. To fight these symptoms effectively, most doctors prescribe Brufen 400 mg, one of the most popular NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) used to give immediate relief from fever and body aches.
This comprehensive manual will educate you on how Brufen 400 mg operates for fever, when and how to take it, proper dosage, side effects, precautions, and anything else you need to know to safely and effectively control fever.
What Is Brufen 400 mg?
Brufen 400 mg is a brand name product that contains 400 milligrams of ibuprofen. It belongs to the category of NSAIDs, which are a class of medications that assist:
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Reduce fever (antipyretic)
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Alleviate pain (analgesic)
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Control inflammation (anti-inflammatory)
Ibuprofen is usually suggested for quick relief from mild to moderate fever, particularly when it occurs with muscle pains, sore throat, or general sickness.
How Does Brufen 400 mg Work for Fever?
Brufen (ibuprofen) functions by preventing cyclooxygenase enzymes (COX-1 and COX-2), which are involved in producing prostaglandins — chemicals that cause fever, pain, and inflammation in the body.
By reducing prostaglandin production, Brufen helps:
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Lower body temperature
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Alleviate chills and sweating
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Relieve headaches and body aches that accompany fever
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Enhance comfort during recovery from viral or bacterial infections
When Should You Take Brufen 400 mg for Fever?
You should consider taking Brufen 400 when:
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Your body temperature rises above 100.4°F (38°C)
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You have fever accompanied by muscle aches or fatigue
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You’re experiencing flu-like symptoms or viral infections
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Over-the-counter paracetamol (acetaminophen) is ineffective
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A doctor recommends it for managing post-vaccination fever or inflammation
Important: Brufen is normally acceptable for short-term use in fever. Always consult a doctor's recommendation for long-term or repeated fever.
Common Conditions with Fever Where Brufen 400 May Help
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Viral infections (cold, flu, COVID-19)
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Bacterial infections (strep throat, tonsillitis)
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Post-surgical fever
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Vaccination-related fever
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Fever with inflammation (like in arthritis or infections)
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Febrile body aches and headaches
Brufen 400 mg Dosage for Fever
For Adults:
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Standard Dose: 400 mg every 6 to 8 hours as needed
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Maximum Dose: Do not exceed 1200–2400 mg/day without medical supervision
Not recommended for:
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Children under 12 (without doctor’s advice)
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Pregnant women in the third trimester
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People with ulcers, kidney/liver issues, or NSAID allergies
Always take Brufen 400 after food to minimize stomach upset.
How to Take Brufen 400 Safely for Fever
Do’s | Don’ts |
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Take after meals | Don’t take on an empty stomach |
Drink plenty of water | Don’t exceed the prescribed dosage |
Follow doctor’s advice | Don’t combine with alcohol or other NSAIDs |
Monitor temperature regularly | Don’t use it for more than 3 days without advice |
Rest and stay hydrated | Don’t use with blood thinners unless approved |
How Long Does Brufen Take to Reduce Fever?
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Onset of Action: 30–60 minutes
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Peak Effect: 1–2 hours
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Duration of Action: 6–8 hours
If fever persists after 3 days of use, consult your healthcare provider.
Brufen 400 vs. Paracetamol for Fever: Which Is Better?
Criteria | Brufen 400 mg (Ibuprofen) | Paracetamol (Acetaminophen) |
---|---|---|
Antipyretic Effect | Strong | Moderate |
Anti-inflammatory | Yes | No |
Pain Relief | Effective | Moderate |
Stomach Safety | May cause irritation | Generally safe |
Use in Pregnancy | Avoid in 3rd trimester | Safer option |
Best Use:
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Brufen is preferred when fever is associated with inflammation and body aches.
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Paracetamol is better for individuals with sensitive stomachs or mild fevers.
Can You Combine Brufen 400 with Paracetamol?
Yes, in certain cases, alternating ibuprofen (Brufen) with paracetamol can be more effective in controlling stubborn or high fevers. However, you must:
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Space them out by 4–6 hours
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Avoid overlapping doses
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Consult your doctor for the right schedule and dosage
Potential Side Effects of Brufen 400 mg
Like any medicine, Brufen 400 mg can cause side effects, especially with prolonged or incorrect usage.
Common Side Effects:
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Nausea or vomiting
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Stomach pain or indigestion
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Headache
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Dizziness
Serious (but rare) Side Effects:
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Gastric ulcers or bleeding
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Kidney issues
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Liver damage
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Increased blood pressure
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Allergic reactions (rash, difficulty breathing)
Seek immediate medical help if you experience black stools, vomiting blood, or shortness of breath.
Who Should Avoid Brufen 400 mg?
Avoid Brufen 400 if you:
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Have a history of gastric ulcers or bleeding
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Suffer from kidney or liver disease
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Are pregnant or breastfeeding (unless advised)
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Are allergic to aspirin or other NSAIDs
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Have asthma triggered by NSAIDs
Safe Alternatives to Brufen for Fever
If Brufen is not suitable for you, try these alternatives:
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Paracetamol (Crocin, Tylenol)
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Acetaminophen + caffeine combinations
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Cold compress to lower body temperature
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Hydration with electrolyte solutions
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Rest and immune-boosting foods (soup, fruits, herbs)
Tips to Manage Fever Alongside Brufen Use
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Stay hydrated – Drink 2–3 liters of fluids daily
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Rest adequately – Allow your body to fight the infection
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Monitor your temperature every 4–6 hours
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Wear light clothing to reduce overheating
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Use cool compresses for comfort during high fever spikes
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Avoid self-medicating for more than 3 days
FAQs About Brufen 400 for Fever
Q1. Can Brufen be taken during COVID-19 fever?
Yes, Brufen 400 can be used to manage fever and body aches during COVID-19, unless contraindicated. However, consult your doctor.
Q2. Can I take Brufen 400 on an empty stomach?
No. Always take Brufen after food to avoid gastrointestinal issues.
Q3. How many times a day can I take Brufen for fever?
You can take 400 mg every 6–8 hours, not exceeding 3–4 doses a day unless advised.
Q4. Is Brufen safe for kids with fever?
Only under pediatric supervision. For children, lower doses of ibuprofen suspension are recommended.
Q5. What should I do if the fever doesn’t go down after taking Brufen?
Consult a healthcare provider. Persistent fever could indicate an underlying infection that needs antibiotics or further evaluation.
Conclusion
Brufen 400 mg is a strong, fast-acting NSAID that offers effective fever relief along with its symptoms such as headache, body pains, and inflammation. Properly used, it brings down high body temperatures and general discomfort.
Its use should nonetheless be cautious and always based on medical recommendation, particularly for people with medical conditions or chronic fevers.
If you need a trusted solution to treat fever, Brufen 400 mg is your best bet—safe, effective, and easily available.